กรมวิทยาศาสตร์การแพทย์
Department of Medical Sciences
ทะเบียนองค์ความรู้ ประสิทธิภาพของการทำแห้งและ ความคงตัวทีสภาวะเร่งของวัคซีนหัดอ้างอิงมาตรฐาน (ภาษาไทย) Efficiency of Freeze-Drying and Stability in Stress Conditions of Measles Vaccine Reference Standard (ภาษาอังกฤษ)
Vaccine reference standards are used by a national control laboratory for quality control of vaccine
products. The purpose is to use vaccine reference standard calibrated against an international reference standard for being control of testing results in laboratory. Therefore testing vaccine samples should always be tested in parallel with a vaccine reference standard. In this study a measles virus vaccine was prepared in the laboratory by virus cultivation on monolayer of Vero cells and a known viral titer was formulated with a suitable formula of the freeze-drying process in order to store it for a long time. After freezedrying